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[67] studied a cohort of over 400,000 T2DM patients above the age of 65 and found that DPP-4i were associated with a 21% decrease in the risk of MACEs (including myocardial infarction and ischemic stroke) with a 46% overall decrease in risk of all-cause mortality

When melanin is unevenly distributed, collagen has depleted, the dermis is dehydrated or micro-circulation is poor, skin appears dull, flat and tired regardless of how much skincare you apply

Your provider can look for other causes things like nutrition gaps, hydration, sleep, or other conditions and may suggest simple bloodwork to check

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You know, I spent decades of my life competing professionally in Iron Man Triathlon, Spartan obstacle course racing, and ultra endurance events