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These businesses dominate the market with billions of dollars in annual revenue, controlling a significant portion of what consumers eat and drink

It is not a direct pharmacologic effect on the face

While offering a much-need treatment option for patients, this class of drugs rang alarm bells for payers once the budget impact was calculated at an annual cost of nearly $18,000, based on wholesale acquisition cost combined with an adult obesity prevalence rate of 41.9% in 2017 (National Health and Nutrition Examination Survey, 2020)

Significant progress has been made in identifying nuclei in the hypothalamus and brainstem and their role in initiating and terminating meals that determine energy balance and body weight regulation [7]