The 15mg dose in SURMOUNT-1 produced the 22.5% average body weight reduction, but this was measured at week 72, so the full effect takes time
However, studies also suggest they might be slightly less effective for weight loss than their injectable counterparts
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Cardiometabolic benefits, such as better blood pressure and cholesterol, can also fade over time once treatment is stopped Lingering side effects Side effects do not vanish immediately
It is a symptom I dont often hear about, but it does occur