Nat Rev Endocrinol 8:728742 Mentzer RM Jr, Bartels C, Bolli R, Boyce S, Buckberg GD, Chaitman B, EXPEDITION Study Investigators et al (2008) Sodium-hydrogen exchange inhibition by cariporide to reduce the risk of ischemic cardiac events in patients undergoing coronary artery bypass grafting: results of the EXPEDITION study
GLP-1 receptor agonists are not appropriate in certain situations, including: Personal or family history of medullary thyroid carcinoma (MTC) History of multiple endocrine neoplasia syndrome type 2 (MEN2) Pregnancy or breastfeeding Known hypersensitivity to the medication History of pancreatitis (relative contraindication

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Physicians also are not legally required to report adverse events to the FDA