Compliance with regional regulations such as EU Annex III or US FDA GRAS status
doi: 10.1016/j.jss.2008.08.003 94 StachelIGeismannCAdenKDeisingerFRosenstielPSchreiberSet al
For LigandScout-based pharmacophore screening (Wolber & Langer, 2004) libraries were converted to ldb format using the idbgen utility, applying the icon best preset and more (600) conformers to ensure adequate sampling of ligand flexibility
Site-specific proteolysis of the fusion protein with PreScission Protease (GE Healthcare, #270843) was conducted for separation of the Sirt4 protein from the GST tag
Since glutathione is the bodys master antioxidant and pretty much the strongest detoxifier, its role in human health is undeniable
Liebold I, Jawazneh AA, Hamley M, Bosurgi L