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Larger, earlystage clinical trials are now needed to determine whether these promising signs actually translate into tangible benefits for patients. Key Questions Answered: Q: If Ozempic or Wegovy reduces amyloid, why didnt human trials show cognitive improvement yet

M.HartmannB.et al (2015)

In US POINTER, the improvements were equivalent to approximately one to two years of cognitive advantage, which came alongside other benefits, including reducing frailty and sleep apnoea and improving blood pressure control

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Publications report a potentially important role in diseases such as Alzheimer's, where liraglutide has been shown to prevent tau tangles in a mouse model (206)

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