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Chaperone proteins, carboxypeptidase E (CPE) (44) and sortilin (14), are two additional receptors of BDNF

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Further studies have shown that HFD can reduce the expression of GLP-1 receptors in the liver, while supplementation with butyrate, a GLP-1 sensitizer, upregulates the levels of GLP-1 receptors in the liver, which stimulates AMPK phosphorylation (69)