The Liraglutide Effect and Action in Diabetes: Evaluation of Cardiovascular Outcome Results trial (LEADER) led to a paradigm shift in the wider use of GLP-1RA from promising antihyperglycemic agents to cornerstone cardiometabolic therapies, demonstrating the significant reduction of major adverse cardiovascular events (MACE) with the use of liraglutide in the population with type 2 diabetes mellitus (T2DM) [12, 13]
Bode H.P., Moormann B., Dabew R., Goke B
The damage to DNA caused by ROS involves mispairing mutation or transversions (G-T) (Higinbotham et al., 1992
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4.1. Vitamin C
[DOI] [PubMed] [Google Scholar] [6].Bannai S, Christensen HN, Vadgama JV, Ellory JC, Englesberg E, Guidotti GG, et al
