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This included Israel Simon Kleiner and Samuel Meltzer, two American physiologists, based at the Rockefeller University in New York who in 1915 demonstrated with animal experiments the power of intravenously administered pancreatic extracts in lowering blood sugar

As researchers learn more about how these medications work, they're becoming increasingly optimistic about improving the lives of people with chronic kidney disease

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They can provide improved blood sugar regulation, assist with sustained weight loss, and might even reduce the risk for cardiovascular disease