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Adults with a body mass index of at least 27 who initiated injectable semaglutide or tirzepatide between July 1, 2022 and December 31, 2024, were eligible

The lyophilization (freeze-drying) process removes all the water, leaving behind a very small, compact puck or even just a light film of white powder at the bottom of the vial

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This is a huge cost burden that ultimately may stop people from accessing the medication they need and worsen health outcomes. Key insights from the new report include: More people are losing coverage: In 2025, the number of people without commercial insurance coverage for these medications surged significantly

Currently, the only remedy for this is pain medication

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