Migrated cells on the lower surface of the membrane were observed using a bright-field light microscope (Zeiss AxioPhot) and quantified by counting cells in multiple representative fields using ImageJ software
Meta-analytic data indicate that tinnitus patients with normal hearing thresholds often exhibit significantly reduced ABR wave-I amplitudes, consistent with synaptic loss, and an increased wave-V/I ratio, suggesting central gain enhancement, although changes in wave-V amplitude are inconsistent across studies 43,63
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Early measurable changes Blood GSH increases observed in RCT data at 1 month (Richie et al.)
GSTT1 (Glutathione S-Transferase Theta 1) is expressed in erythrocytes, liver, and peripheral tissues
In turn, the release of the aforementioned cytokines results in endothelium and platelet activation and, consequently, an increase in NO synthesis and vasodilation, leading to clinical manifestation of migraine [16]