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Human and animal studies on each constituent compound may offer some insights

Preclinical evidence of Alzheimers disease in persons homozygous for the epsilon 4 allele for apolipoprotein E

furthermore, could down-regulate release of proinflammatory Th1 cytokines (i.e., TNF- and IFN-) and stimulate macrophages to generate anti-inflammatory cytokines to minimize the risk of ARDS in COVID-19 691