glp-1 combination therapy WITH RECEPTOR AGONIST AND SGLT2 INHIBITOR fig3.gif

Analytical Workflow Five stages from sample receipt to MoA-annotated deliverable: 1 Sample preparation and quality assessment Drug-treated and control samples (cells, tissue, plasma, or culture supernatant) are processed by established quenching and extraction protocols matched to the sample matrix methanol/water for polar metabolites, MTBE-methanol-water for lipidomic coverage, or a combined biphasic extraction for broadest coverage

disease-specific (B4154) for renal/hepatic

Medication BPC 157 (10 g/kg, 10 ng/kg) was applied either intraperitoneally once time daily (first application immediately after surgery, last at 24 hours before sacrifice) or per-orally in drinking water (0.16 g/ml/12 ml/day till the sacrifice) while controls simultaneously received an equivolume of saline (5 ml/kg) intraperitoneally or drinking water only (12 ml/day)

Tamblyn JA, Pilarski NSP, Markland AD, Marson EJ, Devall A, Hewison M, Morris RK, Coomarasamy A

Heres the formula we use: Total Peptide in Vial: 5mg (which is equal to 5000mcg) Volume of BAC Water Added: This is your variable (e.g., 1mL, 2mL, 2.5mL) Desired Dose: The amount of peptide needed per application for your research protocol

Purple grape juice improves performance of recreational runners, but the effect is genotype dependent: a double blind, randomized, controlled trial