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From a nutritional standpoint, moringa leaves contain: Polyphenols and flavonoids plant-based antioxidants thought to reduce oxidative stress Isothiocyanates sulphur-containing compounds with potential anti-inflammatory properties Chlorogenic acid also found in coffee, and studied for its possible role in glucose metabolism Vitamins and minerals including vitamin C, vitamin A, calcium, and iron The proposed mechanisms by which moringa might influence body weight include modulation of fat metabolism, reduction of inflammation associated with obesity, and potential effects on blood glucose regulation

Statements Author contributions XZ and MW mainly wrote and revised the manuscripts, and constructed the framework of the manuscript

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Patients should avoid extreme temperature changes when possible and be particularly cautious in cold weather, as reduced cold tolerance may increase risk of hypothermia during prolonged exposure

Finally, publication bias cannot be excluded, especially given the increasing clinical interest in GLP-1RAs and the greater likelihood of publishing studies with favorable outcomes

See TABLES 2 and 3 for additional counseling points for patients prescribed GLP-1 therapy