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Pellagra can be prevented by about 11 mg NE/day, but 12 mg to 16 mg NE/day has been found to normalize the urinary excretion of niacin metabolites (breakdown products) in healthy young adults

Regulating Homocysteine Levels: High homocysteine is a common issue for those with an MTHFR mutation, and elevated levels are associated with a higher risk of cardiovascular disease

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The numbers below are purely a reconstitution/concentration reference for handling a lyophilized vial in the lab: a 5 mg vial in 2 mL of bacteriostatic water is 2.5 mg/mL