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Finally, a long time production phase step (about 5 s for the Coarse-Graining model for the aggregation simulation and about 15 s for the Coarse-Graining model for the deaggregation simulation) was carried out in a time step of 20 fs under NPT ensemble

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Karaplis AC, Deckelbaum RA

Campbell RN, Greathead AS, Myers DF, de Boer GJ

PMID: 58 ZhangRLahensNFBallanceHIHughesMEHogeneschJB

Its wise to be cautious when introducing other potent actives