Mice were monitored for 24 h post-surgery for signs of distress (e.g., reduced activity, abnormal grooming, or labored breathing)
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However, the SAMP, N-(4-hydroxy-3-((2-oxoethyl)thio)phenyl)acetamide and 2-(5-Acetamido-2-hydroxyphenyl)sulfanylacetic acid metabolites, observed in the liver models and in vivo, could be generated in presence of all bacterial strains, and in some cases at higher levels compared to the liver models ( i.e., higher production of SAMP by E.coli and of N-(4-hydroxy-3-((2-oxoethyl)thio)phenyl)acetamide by E
Bojkowski CJ, Arendt J, Shih MC, Markey SP
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