Combined Approaches (Neelakantan et al., 2022): NNMT inhibition with reduced-calorie diet produced dramatic adiposity reduction in DIO mice, normalizing metabolic parameters and establishing a distinct gut microbiome
This is particularly relevant for people taking weight loss injections, such as GLP-1 agonists (e.g., Ozempic or Mounjaro), which can sometimes cause fatigue and a feeling of low energy
In fact, there are no NICE guidelines relating to Pernicious Anaemia, just a Clinical Knowledge Summary which has a glaring error in it (weve pointed this out to NICE who are considering revising it)
It is also worth considering for people who want to avoid systemic hormonal changes
Why this belongs in a clinic Every risk above is reduced by the same things: the right needle, a clean field, correct site selection, a steady pace, and a single-use needle each time
Health Conditions Certain health conditions, such as digestive disorders (like Crohn's disease or celiac disease), can impair the absorption of B12