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In contrast, soluble RAGE is thought to be protective, as it retains the ability of ligand binding while lacking signaling function [58]

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The key players in nonvesicular pathways are lipid transfer proteins (LTPs), which shuttle lipids across the aqueous cytosol, often at membrane contact sites (MCSs) where two organelle membranes are tethered only tens of nm apart

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AMPK: AMP-activated protein kinase

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