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As a synthetic analogue of pineal Epithalamin, the peptide is proposed to influence melatonin secretion and normalise circadian and neuroendocrine function in aged animals

The intestinal riboflavin uptake process is also inhibited by chlorpromazine (a tricyclic phenothiazine drug), a compound that shares structural similarities with riboflavin (25)

ROS generated after the formation of ceramide or after an increase in energy metabolism induced by several receptor-interacting protein kinases (RIPs), either in the mitochondrial ETC and/or by NOXs, have been reported to enhance necroptosis 123,124,125

The principal