glutathione solubility Simplified scheme of action of the enzymes S-transferases Glutathione | 70-18-8

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however, in what seems like a twist of biochemical irony, glutathione (a product of the methionine cycle) is actually needed to maintain the function of this pathway (James et al., 2004

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Additionally, Lys114 and Lys116 form strong hydrogen bonds with the carboxylate groups of glutathione