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In clinical trials, ondemand PT141 has improved distressing low desire (HSDD) in premenopausal women and increased erectile responses in men, with onset typically within about 45 minutes and effects lasting several hours

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Briefly, after enrichment, FoB were washed and resuspended in mannitol and sucrose-BSA (MAS-B) buffer pH 7.2 (70 mM sucrose, 220 mM Mannitol, 10 mM KH 2 PO 4 , 5 mM MgCl 2 , 2 mM Hepes, 1 mM EGTA, and 0.4% fatty acid-free BSA), and flux measurements were started

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