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*RDA not established

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Furthermore, studies have shown that the FA metabolites in neutrophils play a chemotactic role in the infiltration of neutrophils into the inflammatory sites, with AA metabolism playing a dominant role (69, 70) Multiple clinical studies have revealed that patients with GA exhibit abnormal AA metabolism, significantly elevated 5-LOX transcription levels, and abnormal increases in LTB4 production, which acts as a neutrophil chemotactic factor (7173)