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Yes, PPIs (such as omeprazole) and H2 blockers (such as famotidine) can be used alongside semaglutide to help manage acid-related disorders and protect the stomach lining in patients with a history of PUD

Teichert J, Kern J, Tritschler HJ

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Metabolic analysis Oxygen consumption rate (OCR) and extracellular acidification rate (ECAR) were measured with a 24-well XF Extracellular Flux Analyzer (Agilent Technologies) and Seahorse Wave Controller Software (Agilent Technologies), according to the manufacturers instructions

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