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Clinical indications include deficiency due to inadequate diet or malabsorption, drug-induced deficiency (for example, from long-term isoniazid or oral contraceptives), and certain inborn errors of metabolism (such as pyridoxine-dependent seizures or sideroblastic anemia)
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Patients should maintain that dose for about one month before attempting to increase the dose again
A role for lactate dehydrogenases in the survival of neisseria gonorrhoeae in human polymorphonuclear leukocytes and cervical epithelial cells