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11,190,192,193 To note, real world observational data suggest that average weight loss is lower than that seen in randomised controlled trials due to a combination of lower achieved dosages, treatment interruptions and high discontinuation rates (up to 2050% within the first year)

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doi: 10.1097/00006842-200111000-00016 59 Fernandez-RealJ-MPugeatMGrasaMBrochMVendrellJBrunJet al

The following products were obtained (Table 1): According to the General Procedure D, molecules 6a i were reacted

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