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Committee for the Update of the Guide for the Care and Use of Laboratory Animals, Institute for Laboratory Animal Research (U.S.) & National Academies Press (U.S.)

First, the increased food intake evoked by energy loss during SGLT2 inhibition could partly be prevented by an appetite-reducing therapy

Since the latter study had a placebo group which had redox and methylation biomarkers measured at the beginning and end of the intervention, we use this placebo group as a control group for all three studies in order to determine if the changes in redox and methylation metabolism were significant as a result of the three interventions

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