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This creates an elevated TIMP to MMP ratio that correlates with collagen and elastin synthesis stimulation

10.1371/journal.pone.0296259 35 EsfandyariS.ElkafasH.ChughR

It is present in various cells, including macrophages, endothelium, smooth muscle cells, and respiratory epithelium

218 It also reduced ROR t, IL-17, IL-23, miR-141, miR-155, miR-200, and symptoms in AS patients

Senapati J , Ravandi F, Almanza E, Kadia TM, Montalban-Bravo G, Faderl S, Sasaki K, Short NJ, Daver N, DiNardo CD, Masarova L, Ferrajoli A, Haddad FG, Jabbour E, Borthakur G, Tan S, Pierce S, Garcia-Manero G, Andreeff M , Valero YA