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The anti-amyloid monoclonal antibody lecanemab: 16 cautionary notes

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Single nuclei isolation For Multiome sequencing (snRNA-seq+snATAC-seq), nuclei were isolated with Nuclei Lysis buffer [10 mM Tris-HCl, 10 mM NaCl, 3 mM CaCl 2 , 0.1% NP-40, 0.1% Tween-20, 1% BSA, 1 mM DTT, all in 1x PBS supplemented with RNase inhibitor (1U/L, Sigma)]