L-carnitine dapat membantu menunda kelelahan selama berolahraga dengan meningkatkan penggunaan energi aerobik dan mengurangi akumulasi asam laktat
M., Buranasudja, V., Wagner, B
Urolithin A improves muscle function by inducing mitophagy in muscular dystrophy
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Disruption in iron homeostasis, including increased transferrin receptor expression and ferritin degradation via NCOA4-mediated ferritinophagy, contributes to ferroptotic susceptibility ( Lipid Peroxidation: Polyunsaturated fatty acids (PUFAs), especially arachidonic and adrenic acids, are substrates for lipoxygenases (LOX), which drive peroxidation in membrane phospholipids, generating cytotoxic lipid peroxides such as 4-hydroxynonenal (4-HNE) and malondialdehyde (MDA) ( Glutathione Depletion and GPX4 Inactivation: System Xc imports cystine for GSH synthesis
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