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The central mechanism involves decreased dopamine and norepinephrine signaling in the hypothalamus, where these neurotransmitters are produced and released during sexual excitation

Wharton S, Liu A, Pakseresht A, Nrtoft E, Haase CL, Mancini J, Power GS, Vanderlelie S, Christensen RA

My experience at the NIH was a tremendous inspiration