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OLGs have to keep constant contact with axons in order to regulate OPC growth, differentiation, and myelination, which decreases myelin formation and axonal function due to OPC and OLG damage, thus interfering with neuronal connectivity and function

Antioxid Redox signal 2007

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As previously described 43 , a pentabasic motif is retained in all classes of pro-IGF-I which contains two putative cleavage sites recognized by PCs, Arg71 and Arg77

Hyaluronic acid is a gel-like substance naturally found throughout our bodies, with the highest concentrations in our joints, eyes, and skin