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They come from the peer-reviewed literature, including the researchers who conducted the bone density studies cited earlier in this article

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New studies showed that semaglutide (Ozempic) may help reduce the progression of kidney disease in people with type 2 diabetes, and it may also help protect kidney function in people who are overweight or obese with established cardiovascular disease

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Four studies (36%) reported elevated opioid peptide levels (Pedersen et al