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7 Pooyandjoo M, et al

Analysis of the ability of pramlintide to inhibit amyloid formation by human islet amyloid polypeptide reveals a balance between optimal recognition and reduced amyloidogenicity

Many people experience them most intensely at the start of treatment or after a dose increase, and then notice improvement as the body adjusts

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In comparison, medications like semaglutide, with a longer half-life, stay for a long time in the body and only need to be taken once weekly