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H 2 S: a novel gasotransmitter that signals by sulfhydration

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These data strongly suggest the idea that resistance is not only due to a mutation in a target gene but also to a more wide cellular re-organization ranging from proteomic modulations as those observed in cell wall of resistant cells [24], [25] to metabonomic variations as those related to increased levels of intracellular GSH

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Evidence linking protein misfolding to quality control in progressive neurodegenerative diseases