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The longest clinical trial for NR, involving 10 A-T patients, assessed the effects of up to 500 mg per day of NR supplementation over two years

Its liver benefits come indirectly through weight loss and metabolic improvement

PLoS ONE 9:e100897

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Plan and approach We created a structured plan to (1) identify applications, (2) retrieve primary trials, (3) extract outcomes, (4) organize evidence into a summary artifact, and (5) synthesize the final answer

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