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Mayo Clinic proceedings , 86 (7), 673680

While we are still a long way away from pinpointing an analogous pathogenic species in MS, once identified, a specific immunotherapy targeting the relevant misfolded proteins, rather than downstream immune effectors as is the current approach, could be more effective in the progressive stages of MS

"Instead of half the pie, you're going to do one slice of pizza and you're going do a side salad

For mass spectrometry analysis, the AB QTRAP 5500 triple quadrupole mass spectrometer equipped with an ESI ion source was utilized in multi-reaction monitoring (MRM) mode