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Complement C1q drives microglia-dependent synaptic loss and cognitive impairments in a mouse model of lipopolysaccharide-induced neuroinflammation

General qualifying criteria include: Adults with a BMI of 30 or higher (clinical obesity), or BMI of 27 or higher with at least one weight-related health condition such as type 2 diabetes, high blood pressure, or high cholesterol Adults who have not achieved adequate weight loss through diet and lifestyle changes alone Patients without a personal or family history of medullary thyroid carcinoma or multiple endocrine neoplasia syndrome type 2 Patients who are not pregnant or planning pregnancy Patients without a history of pancreatitis (assessed case by case) At your consultation, Tiffany reviews your health history, discusses your weight loss goals and previous experiences, and determines whether GLP-1 therapy is appropriate for you and which medication and dosing approach makes the most sense

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eating right away means your stomach receives a dual assault of food volume and heightened GLP-1 signaling