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On the other hand, research by Micic et al

It also reduces the release of proinflammatory factors by blocking the MAPK/ERK pathway activated by S100 calciumbinding protein A8/A9 (S100A8/A9) and HMGB1

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Important: If you experience a severe allergic reaction, such as swelling of the lips, face, or tongue, trouble breathing, wheezing, or widespread hives, call 911 or go to the nearest ER immediately