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10.1093/humrep/dem408 74 HaraguchiH.HirotaY.Saito-FujitaT.TanakaT.Shimizu-HirotaR.HaradaM.et al (2019)

Several studies have shown microbial alterations in MALFD, alcoholic liver disease and acute-on-chronic liver failure which also evolve with disease severity (158162)

IL, Interleukin

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It is the crux of this article

Combining both agents could theoretically amplify appetite suppression and gastrointestinal effects, though long-term safety data on this specific combination is lacking