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Spiewak, M

This can result in an increased risk of an array of conditions like: Anxiety Depression Bipolar Disorder Schizophrenia Obsessive Compulsive Disorder May Be Associated With Autoimmune Conditions [Ref] Vitamin B12 deficiency, improper folate metabolism and homocysteine imbalance are common with MTHFR mutations

The other change is cumulative UV damage

Exposure to UV light and atmospheric oxygen generates reactive oxidative species that convert tryptophan's indole ring into oxidized products (kynurenine pathway derivatives and others)

Does semaglutide make COVID-19 worse or increase hospitalization risk