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Results GSTM2 was upregulated in hepatic tissues of mice fed HFD and MCDD The high-fat diet and methionine choline deficient diet were used to make hepatic steatosis

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Its anti-inflammatory mechanisms include reducing TNF-alpha production, downregulating NF-kB activation, and decreasing oxidative stress through enhanced antioxidant enzyme activity

EVIDENCE ASSESSMENT: NO RENAL SIDE EFFECTS AT ORAL DOSES No peer-reviewed study has demonstrated that oral glutathione at standard doses causes kidney damage or measurable side effects in individuals with normal renal function

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