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Kristensen SL, Rrth R, Jhund PS et al

Over-the-counter remedies may be appropriate in some cases, but should only be used after discussion with a pharmacist or GP: Oral rehydration salts (such as Dioralyte) are recommended for diarrhoea-related fluid loss Loperamide may be considered for short-term management of loose stools, but must be avoided if you have a fever, blood or mucus in your stools, or if antibiotic-associated diarrhoea (including Clostridioides difficile ) is suspected seek pharmacist or GP advice first For constipation, macrogol-based laxatives (such as Movicol) are a reasonable first-line option in line with NICE CKS guidance on constipation in adults

The aim of this study was to determine age- and sex- specific reference percentile values and z-scores of GLP-1, GIP and glucagon in children

Starting near the higher end increases the risk of gastrointestinal discomfort and other tolerability issues

The American Diabetes Association (ADA) and American College of Cardiology (ACC) recommend a multifaceted approach that extends beyond glycemic control

These side effects commonly initiated at treatment onset and abated with continued use as the body acclimated to the drug