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This explains a higher incidence of long-term effects in neonatal sepsis survivors but also underlines the importance of different strategies for sepsis treatment both with antioxidant administration and pharmacologic inhibition of pro-oxidant pathways in addition to antibiotics

362 NAD + deficiency correlates with disturbed circadian clocks during aging Besides mitigating the oxidative damage, NAD + can extend lifespan by driving the circadian rhythms