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In a clinical trial on 6 men, drinking coffee (165-400 mL/day) increased gallbladder contractions and the levels of the hormone that stimulates bile release (cholecystokinin) [2, 21]
*Correspondence: Gilda Varricchi, [email protected] This article was submitted to Cancer Immunity and Immunotherapy, a section of the journal Frontiers in Immunology ORCID: Remo Poto, orcid.org/0000-0002-4723-0167
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This means it generally doesn't cause a notable increase in cortisol, prolactin, or aldosterone levels
10.1016/j.pneurobio.2010.10.007 101 RamalingamP.PoulosM