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As noted previously, increasing age is linked to reduced GSH levels (Drge, 2002a,b), which can be the result of extensive GSH oxidation and/or reduced pool of cell thiols, and cysteine (whey protein) administration enhances GSH levels and increases longevity (Bounous et al., 1989
SCD patients have aberrant metabolic regulation of fumarate, glutamate, glycine, malate, and other metabolites involved in glycolysis, nucleotide catabolism, and glutathione metabolism 3,4,5,6
Ubiquitination flow repressors: enhancing wound healing of infectious diabetic ulcers through stabilization of polyubiquitinated hypoxia-inducible factor-1 by theranostic nitric oxide nanogenerators
Mol Brain Res 15: 207215
A 2018 meta-analysis of 132,738 mother-child pairs found associations that increased with longer exposure duration