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This underdiagnosis can lead, besides death in 20% when it is not appropriately treated, to Korsakoffs syndrome, a severe dysfunction often following untreated Wernickes encephalopathy, that does not remit even with thiamine treatment and is associated with chronic alcohol abuse and chronic thiamine deficiency (40, 42)

Ireland PJ, et al, Appl Clin Genet

Some people may see better results with Wegovy: almost a third of people in its trial lost 25% or more of their starting weight after a year on the maximum 7.2mg dose

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