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Symptoms of B12 deficiency include: Low energy and fatigue Digestive problems Depression and moodiness Insomnia Brain fog and memory loss Anemia Reduced immune system function Tingling or numbness in the extremities Swollen tongue Loss of vision or hearing Jaundice Kidney disease Pale skin Poor circulation in the extremities If you are over age 50 and are experiencing one or more of the above symptoms, boosting your intake of B12 cannot hurt, and it may provide a safe and inexpensive solution while preventing a wrong diagnosis

Disadvantages: Absorption : Oral supplements may have lower absorption rates compared to injectables due to digestive system breakdown

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The paper emphasizes that the origin of malignant melanoma is due to sun burns in people who spend most of their time indoors, only getting sun exposure in excessive amounts over holidays (intermittent exposure)