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Though Retatrutide is not yet FDA-approved, its potential effectiveness shows great promise, as evidenced by the TRIUMPH-1 Phase 3 trials that demonstrated up to 28.3% weight loss over 80 weeks

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In contrast, higher abundances of Actinomyces , Eggerthella , Clostridium Cluster XlVa, and Lactobacillus were observed in OP patients relative to those with normal bone mineral density (BMD) (62)