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doi:10.1038/s41591-024-02970-5 PubMed: This substudy demonstrated that retatrutide reduced liver fat by 81-82% at the 8mg and 12mg doses over 24 weeks, providing evidence of retatrutides multi-system metabolic benefits beyond weight loss

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In stroke models, it reduces hippocampal neuron loss, restores memory, and improves motor coordination by modulating gene expression and reducing inflammation

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